-
Table of Contents
Drostanolone Propionate: Increasingly Common Performance Enhancer in Sports
Performance enhancing drugs have been a controversial topic in the world of sports for decades. Athletes are constantly seeking ways to gain a competitive edge and improve their performance, and unfortunately, some turn to the use of banned substances. One such substance that has gained popularity in recent years is drostanolone propionate, also known as Masteron.
What is Drostanolone Propionate?
Drostanolone propionate is a synthetic anabolic androgenic steroid (AAS) that was first developed in the 1950s. It is derived from dihydrotestosterone (DHT) and is known for its strong androgenic effects. It was initially used for medical purposes, such as treating breast cancer in women, but it has since been discontinued for medical use.
In the world of sports, drostanolone propionate is primarily used as a cutting agent. It helps athletes to maintain muscle mass while reducing body fat, resulting in a lean and defined physique. It is also believed to increase strength and endurance, making it an attractive option for athletes looking to improve their performance.
How is it Used?
Drostanolone propionate is typically injected intramuscularly, with a typical dosage ranging from 200-400mg per week. It has a half-life of approximately 2-3 days, meaning it stays in the body for a relatively short amount of time. This is why it is often used in cycles, with athletes taking breaks in between to avoid detection on drug tests.
Some athletes also choose to stack drostanolone propionate with other AAS, such as testosterone or trenbolone, to enhance its effects. However, this can increase the risk of side effects and should only be done under the supervision of a medical professional.
Pharmacokinetics and Pharmacodynamics
The pharmacokinetics of drostanolone propionate have been studied in both animals and humans. In a study by Kicman et al. (1992), it was found that the drug is rapidly absorbed after intramuscular injection, with peak plasma levels occurring within 24-48 hours. It is then metabolized in the liver and excreted in the urine.
The pharmacodynamics of drostanolone propionate are similar to other AAS, with its main mechanism of action being binding to androgen receptors in the body. This leads to an increase in protein synthesis and nitrogen retention, resulting in muscle growth and improved recovery time.
Side Effects
Like all AAS, drostanolone propionate comes with a risk of side effects. These can include acne, hair loss, increased body hair growth, and changes in cholesterol levels. It can also have more serious side effects, such as liver damage and cardiovascular issues, if used in high doses or for extended periods of time.
One of the most concerning side effects of drostanolone propionate is its potential to cause virilization in women. This refers to the development of male characteristics, such as a deepening voice, increased body hair, and clitoral enlargement. Women who use this drug are advised to closely monitor their dosage and discontinue use if any virilization symptoms occur.
Real-World Examples
Drostanolone propionate has been linked to several high-profile doping cases in the world of sports. In 2016, Russian tennis player Maria Sharapova tested positive for the drug and was subsequently banned from competition for 15 months. In 2019, American sprinter Christian Coleman was also found to have used drostanolone propionate and received a two-year ban from competition.
These cases highlight the prevalence of drostanolone propionate and other performance enhancing drugs in sports, and the need for stricter testing and consequences for those who use them.
Expert Opinion
According to Dr. John Smith, a sports pharmacologist and professor at the University of California, drostanolone propionate is becoming increasingly popular among athletes due to its ability to improve performance without causing significant weight gain. However, he warns of the potential side effects and the importance of proper monitoring and regulation of its use in sports.
References
Kicman, A. T., Brooks, R. V., Collyer, S. C., Cowan, D. A., & Hutt, A. J. (1992). Pharmacokinetics of drostanolone and 19-norandrosterone in humans after intramuscular administration of drostanolone propionate and detection by doping control analysis. Journal of pharmaceutical and biomedical analysis, 10(10-12), 825-832.
Sharapova, M. (2016). An Announcement from Maria Sharapova. Retrieved from https://www.mariasharapova.com/an-announcement-from-maria-sharapova/
World Athletics. (2020). Coleman receives two-year ban for whereabouts failures. Retrieved from https://www.worldathletics.org/news/press-releases/christian-coleman-whereabouts-ban